A biomimetic synthetic feeder layer supports the proliferation and self-renewal of mouse embryonic stem cells
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چکیده
منابع مشابه
The effect of BMP4 on mouse embryonic stem cell proliferation and differentiation into primordial germ cells
Background and Aim: Artificial gamete production from stem cells is a novel strategy for treatment of infertility. Among various stem cell sources, embryonic stem cells (ESC) can be considered as an appropriate source for in vitro formation of germ cells. In this study we evaluated the effect of BMP4 on proliferation and differentiation of mouse embryonic stem cells into primordial germ cells (...
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Background and Aim: Embryonic stem cells are identified with two unique characteristics. First, they can be maintained and expanded as pure populations of undifferentiated cells, a characteristic which is known as self renewal aspect of embryonic stem cells. Second, these cells can give rise to all body cell types. In the current study, we used a feeder-free condition to differentiate mouse emb...
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ژورنال
عنوان ژورنال: Acta Biomaterialia
سال: 2016
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2016.04.047